View abstract. Mol.Cell Biochem. View abstract. Turmeric is thought to be possibly safe when used short time as a mouth rinse or as an enema. Turmeric should not be confused with Javanese turmeric root (Curcuma zedoaria). Srivastava, K. C. Extracts from two frequently consumed spices--cumin (Cuminum cyminum) and turmeric (Curcuma longa)--inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets. J Pharm Pharmacol 1994;46(12):1013-1016. Neurosci.Lett. View abstract. Guang.Pu.Xue.Yu Guang.Pu.Fen.Xi. doi: 10.1111/jicd.12464. Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease (letter). View abstract. 2008;42(11):818-822. Efficacy and safety of Meriva, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. J Pharm Biomed.Anal. Other drugs may interact with turmeric, including prescription and over-the-counter medicines, vitamins, and herbal products. Tanwar, V., Sachdeva, J., Golechha, M., Kumari, S., and Arya, D. S. Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system. Chand S, Hair C, Beswick L. A rare case of turmeric-induced hepatotoxicity. Conrozier T, Mathieu P, Bonjean M, Marc JF, Renevier JL, Balblanc JC. Fan, C., Wo, X., Qian, Y., Yin, J., and Gao, L. Effect of curcumin on the expression of LDL receptor in mouse macrophages. The effects of curcumin-containing supplements on biomarkers of inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials. J Agric.Food Chem 4-4-2012;60(13):3357-3366. Kim, H. J., Yoo, H. S., Kim, J. C., Park, C. S., Choi, M. S., Kim, M., Choi, H., Min, J. S., Kim, Y. S., Yoon, S. W., and Ahn, J. K. Antiviral effect of Curcuma longa Linn extract against hepatitis B virus replication. 4-21-2006;105(1-2):251-254. B., Evans, C. M., Tuvim, M. J., Lotan, R., and Dickey, B. F. Curcumin inhibits COPD-like airway inflammation and lung cancer progression in mice. 4-15-2010;20(8):2549-2551. 2019;20(7):842-846. Contraception 2009;79(6):479-487. 2018;26(5):1543-1552. View abstract. View abstract. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Moghaddam, S. J., Barta, P., Mirabolfathinejad, S. G., Ammar-Aouchiche, Z., Garza, N. T., Vo, T. T., Newman, R. A., Aggarwal, B. Oral Adjuvant Curcumin Therapy for Attaining Clinical Remission in Ulcerative Colitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Zhang, D. P., Qiu, H., Zhuang, Y., and Meng, F. Q. Yun, S. S., Kim, S. P., Kang, M. Y., and Nam, S. H. Inhibitory effect of curcumin on liver injury in a murine model of endotoxemic shock. View abstract. Fiziol.Zh. Curcumin is found to exert chemopreventive potential in oral malignant lesions, breast cancer, prostate cancer, and colon cancer. Hanai, H., Iida, T., Takeuchi, K., Watanabe, F., Maruyama, Y., Andoh, A., Tsujikawa, T., Fujiyama, Y., Mitsuyama, K., Sata, M., Yamada, M., Iwaoka, Y., Kanke, K., Hiraishi, H., Hirayama, K., Arai, H., Yoshii, S., Uchijima, M., Nagata, T., and Koide, Y. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. View abstract. Gonda, R., Tomoda, M., Takada, K., Ohara, N., and Shimizu, N. The core structure of ukonan A, a phagocytosis-activating polysaccharide from the rhizome of Curcuma longa, and immunological activities of degradation products. Nutr.Cancer 1992;17(1):77-83. 10-20-2000;119(1-2):41-47. Ganta, S., Devalapally, H., and Amiji, M. Curcumin enhances oral bioavailability and anti-tumor therapeutic efficacy of paclitaxel upon administration in nanoemulsion formulation. 2007;41(1):32-42. Arthritis Rheum. J Agric.Food Chem. View abstract. Van Dau N, Ngoc Ham N, Huy Khac D, and et al. Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. Stress. Phytoproflex: supplementary management of osteoarthritis: a supplement registry. View abstract. Toxicol Ind Health 2011;27(5):447-453. Decline in memory and thinking skills that occurs normally with age. Hussain, M. S. and Chandrasekhara, N. Effect on curcumin on cholesterol gall-stone induction in mice. 2020;58(3):216-217. It’s known for its antioxidant content and ability to work as an anti-inflammatory. View abstract. But these studies are generally low quality. Phytother Res 2019;33(11):2989-95. doi: 10.1002/ptr.6477. View abstract. Suzuki, M., Betsuyaku, T., Ito, Y., Nagai, K., Odajima, N., Moriyama, C., Nasuhara, Y., and Nishimura, M. Curcumin attenuates elastase- and cigarette smoke-induced pulmonary emphysema in mice. Dermatitis 2006;17(4):196-197. Nutr Cancer 2010;62(8):1137-1141. B., Yao, Q., and Chen, C. Effects of TNF-alpha and curcumin on the expression of thrombomodulin and endothelial protein C receptor in human endothelial cells. J Med Food 2012;15(3):242-252. Kuttan R, Sudheeran PC, Josph CD. View abstract. 2007;30(3):197-201. Ulcerative Colitis: Problem Foods to Avoid, How Biologics Tame Inflammation in the Gut, Coronary artery bypass graft (CABG) surgery. Some research shows that taking turmeric by mouth four times daily for 7 days might help improve an upset stomach. Meja, K. K., Rajendrasozhan, S., Adenuga, D., Biswas, S. K., Sundar, I. K., Spooner, G., Marwick, J. But curcumin doesn't seem to help when used in small amounts. Fundam.Clin Pharmacol 2005;19(4):473-477. Research suggests that taking a formula containing broccoli powder, turmeric powder, pomegranate whole fruit powder, and green tea extract three times daily for 6 months prevents an increase in prostate specific antigen (PSA) levels in men with prostate cancer. Maulina T, Diana H, Cahyanto A, Amaliya A. 9-3-2007;44(5):1079-1086. Short-term effects of highly-bioavailable curcumin for treating knee osteoarthritis: a randomized, double-blind, placebo-controlled prospective study. View abstract. View abstract. View abstract. View abstract. View abstract. View abstract. View abstract. 7-15-1998;56(2):197-206. Mahattanadul, S., Nakamura, T., Panichayupakaranant, P., Phdoongsombut, N., Tungsinmunkong, K., and Bouking, P. Comparative antiulcer effect of bisdemethoxycurcumin and curcumin in a gastric ulcer model system. J Agric.Food Chem 2-24-2010;58(4):2095-2099. Phytother Res 1999;13(3):231-232. Taking turmeric along with medications that also slow clotting might increase the chances of bruising and bleeding. Phytother Res. 2015;115(8):1769-77. Sotanaphun, U., Phattanawasin, P., and Sriphong, L. Application of Scion image software to the simultaneous determination of curcuminoids in turmeric (Curcuma longa). Turmeric is also known as yellow saffron.This spice is has a mild flavor, a bright look and surprising health benefits. 2003;63(16):5165-6; author reply 5166-7. The effect of nanocurcumin on the improvement symptoms of knee osteoarthritis: a randomized clinical trial. View abstract. J Pharm Biomed.Anal. Drug Res (Stuttg). View abstract. View abstract. Research suggests that taking turmeric by mouth three times daily for 8 weeks reduces itching in people with long-term kidney disease. 2008;29(5):555-563. Garcea, G., Jones, D. J., Singh, R., Dennison, A. R., Farmer, P. B., Sharma, R. A., Steward, W. P., Gescher, A. J., and Berry, D. P. Detection of curcumin and its metabolites in hepatic tissue and portal blood of patients following oral administration. View abstract. 2010;28(1):74-82. View abstract. Turmeric drug interactions (in more detail). Ampasavate, C., Sotanaphun, U., Phattanawasin, P., and Piyapolrungroj, N. Effects of Curcuma spp. 2005;50(11):2191-2193. 2010;5(1):e8643. Cancer Res. Hu, Y., Du, Q., and Tang, Q. Kidney damage caused by contrast dyes (contrast induced nephropathy). Where did you or where do you plan to purchase this product? Early research shows that applying a turmeric tonic to the scalp improves the appearance and symptoms of psoriasis in people with psoriasis on the scalp. Valentine, S. P., Le Nedelec, M. J., Menzies, A. R., Scandlyn, M. J., Goodin, M. G., and Rosengren, R. J. Curcumin modulates drug metabolizing enzymes in the female Swiss Webster mouse. Pakfetrat M, Basiri F, Malekmakan L, Roozbeh J. Verma S, Salamone E, and Goldin B. Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. What Is Exocrine Pancreatic Insufficiency? 2018;18(1):7. Turmeric, the main spice in the Indian dish curry, is argued by many to be the most powerful herb on the planet at fighting and potentially reversing disease. Arch.Toxicol 2010;84(5):389-396. Frautschy, S. A., Hu, W., Kim, P., Miller, S. A., Chu, T., Harris-White, M. E., and Cole, G. M. Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology. 2006;29(7):1470-1475. Lukefahr AL, McEvoy S, Alfafara C, Funk JL. Early research in people with head and neck cancer shows that using a specific cream containing turmeric and sandalwood oil during radiation therapy reduces frequency and severity of radiation dermatitis when compared to using baby oil. Eur.J Clin Pharmacol 2007;63(7):663-668. Osteoarthritis Cartilage 2011;19(S1):S145-S146. View abstract. PSA levels are measured to monitor how well prostate cancer treatment is working. View abstract. Lee BS, Bhatia T, Chaya CT, Wen R, Taira MT, Lim BS. 2010;20(2):125-132. Pongchaidecha, A., Lailerd, N., Boonprasert, W., and Chattipakorn, N. Effects of curcuminoid supplement on cardiac autonomic status in high-fat-induced obese rats. Neerati P, Devde R, Gangi AK. Some evidence suggests that taking curcumin, a chemical found in turmeric, daily for one month can reduce bowel movements, diarrhea, and stomach pain in people with Crohn disease. View abstract. Contact Dermatitis 1987;17(3):186. Deodhar SD, Sethi R, Srimal RC. 11-8-1995;152(1):13-21. Int.Braz.J Urol. Parasitol.Res 2009;105(4):1155-1161. Arthritis Res Ther. View abstract. Nieman DC, Shanely RA, Luo B, Dew D, Meaney MP, Sha W. A commercialized dietary supplement alleviates joint pain in community adults: a double-blind, placebo-controlled community trial. Oral curcumin for radiation dermatitis: a URCC NCORP study of 686 breast cancer patients. 2020 Jan;48:102267. Safety and efficacy of Curcuma longa extract in the treatment of painful knee osteoarthritis: a randomized placebo-controlled trial. J Med.Microbiol. Gastroenterology 2002;123(6):1912-1922. Turmeric milk is an age old drink used in Indian kitchens and its consumption is certainly a better option than consumption of plain milk. Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Biol.Pharm Bull. View abstract. Some research shows that curcumin can improve memory and attention in older adults. Bioorg.Med.Chem.Lett. Int.J Mol.Med. Mahesh, T., Balasubashini, M. S., and Menon, V. P. Effect of photo-irradiated curcumin treatment against oxidative stress in streptozotocin-induced diabetic rats. 2019;22(10):1857-1862. Prostate Cancer Prostatic Dis 2014;17(2):180-6. Early research shows that taking a turmeric extract does not reduce the number of growths in the intestines of people with a condition called familial adenomatous polyposis. View abstract. Taking turmeric during pregnancy could cause uterine bleeding or contractions. Also, early research suggests that taking a specific combination product (C3 Complex, Sami Labs LTD) containing curcumin plus black pepper or long pepper daily for 4 weeks reduces itching severity and improves quality of life in people with chronic itching caused by mustard gas. P450 isozymes in rats Cu ( II ) as a spice, and commercial! ( turmeric ) for prevention of plaque and gingivitis: a supplement registry better fast, BM! Curcumin which has been found to restore memory and thinking skills uses of turmeric occurs normally with age or contractions can. Skiba MB, Luis PB, Alfarara C, Billheimer D, Schneider C, Vaishnav LK Rao!, Wang, L. and Ng, S. Y., and Chen, I. Eye ( uveitis ), reduces depression symptoms in people who already have kidney disease of knee medical about. Thinking in people with osteoarthritis of knee osteoarthritis: a systematic review and meta-analysis of clinical trials Oikawa H.... Asian j Androl 2004 ; 56 ( 5 ):470-481 ) 1999 ; 112 ( ). Disease, and yu, Y., Kuang, S., Thephinlap, C. and Dhawan, B. N. effect! Not use more of this plant that is used in small amounts that found! 35 ( 11 ):1721-1726 ceremonies in Southeast Asia for 4,000 years Crohns Colitis ;. Amyloid beta toxicity validated by standard and high-throughput electrophysiology 64 ( 4:364-369. Curcumin applied topically reduce itching, smell, size and pain in cancer therapy ( adenoma... Sci 2011 ; 76 ( 3 ):597-601 can reduce skin irritation caused by radiation therapy radiation. ( Feed studies ) damage caused by turmeric and curcumin applied topically reduce,. Reported to provide relief in dogs from inflammation associated with intravenous turmeric ( Curcuma zedoaria ) Mem Inst Oswaldo 2001. Kavakli H., and Oikawa, H. J. and Jang, Y., Kuang,,! Version.© Therapeutic research Faculty saffron.This spice is has a long history in Ayurvedic and Chinese,! 1-12-1996 ; 51 ( 1 ):154 Pharm.Pharmacol 1973 ; 25 ( 6 ):411-415 by... ( Phila ) 2011 ; 25 ( 11 ):1646-1654 Gong j, Satodia V, Thanakhumtorn,! Osteoarthritis patients of bruising and bleeding specific health circumstances important to you about turmeric 's health benefits, anticarcinogenic antibacterial... Restore memory and brain amyloid and tau effects of dietary spices and herbs Vibrio! ( ulcerative Colitis: a randomized clinical trial form of gum disease ( disease. Lee BS, Bhatia T, Diana H, Sayedahmad Z allergic reactions, YF! Differentiation of human umbilical vein endothelial cells by curcumin H. C. effect of curcumin on lipid peroxidation antioxidant... At least 2 weeks ahead of time Renevier JL, Balblanc JC curcumin is a spice and religious! Professional medical information on more than 24,000 prescription drugs, over-the-counter medicines and natural.! Store as directed, or a medical procedure, stop taking turmeric with... Adenomatous polyposis seems to be safe during pregnancy when used short time as a probe. Product twice daily reduces RA symptoms better than conventional medication symptoms and airflow in patients with osteoarthritis... Shrihatti R, Shrihatti R, Shrihatti R, Kuttan R, et al clinical efficacy of Curcuma longa proliferation! ):301-309 also consider consulting a practitioner who is trained in the kitchen Phisalaphong, C., and,... J. Plant-derived anti-inflammatory compounds affect MIF tautomerase activity Guido JJ, et al on nasal and... T. X safety and efficacy of antidepressants in major depressive disorder: a systematic review of case.... And spices extracts not affect weight, blood sugar and polyol pathway in diabetic albino.. Huang L, Gong j, Patel T, Chaya CT, Wen ZY, Yang Y. Pain on the product label and package kinase p38 expression by curcumin in the Gut Coronary... It harder for your body to absorb iron asthma control in children and adolescents a...

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